Background: Lower extremity edema is a problem in patients with advanced cancer, causing decreased physical function and reduced movement.

Methods: Eight patients with advanced cancer were treated by subcutaneous needles inserted in the inner and outer sides of the ankles and attached to an enclosed drainage bag, or by creating subcutaneous tracts in both ankles.

Results: All patients lost weight after 24 hours. A total of 4 patients reported enhanced mobilization and 5 patients had significant improvement of mobilization that improved their quality of life.

Conclusions: Subcutaneous drainage can improve edema in the lower limbs or the lower body segment, contributing to patient comfort at his end-of-life period. A prospective study with better evaluation of patient quality of life is ongoing in our center.